Appendiceal neuroendocrine neoplasms in children and adolescents – Two case reports from a tertiary care center in coastal India

Appendiceal neuroendocrine neoplasms (ANENs) are uncommon in children and adolescents incidentally diagnosed 0.3% of appendicectomy specimens. Pediatric ANENs rarely metastasize have excellent prognosis. We report two cases who presented clinically radiologically with features acute appendicitis for which they underwent appendicectomy. On gross examination, £ 2 cm lesion was identified both the appendix. Microscopic immunohistochemical analysis clinched diagnosis ANENs. Patients were followed up 18 months disease free. This emphasizes that a possibility ANEN should be kept as differential even pediatric population presenting appendicitis. A routine histopathological examination all specimens is therefore crucial, early associated